What things properly predict Atherosclerosis extent? Have a look !

Interesting paper today which is rather...revealing. We all want to know what things drive atherosclerosis & heart disease - and here the authors luckily have CAC measurements (the most powerful indicator of atherosclerosis extent - by a country mile).

Sadly they think that atherosclerosis progression can't be stopped - it's an inevitability in their opinion. How sad to see this, how misguided they are - if only they knew.  Anyway, on to the paper summary: "Progression of coronary artery calcification seems to be inevitable, but predictable - results of the Heinz Nixdorf Recall (HNR) study"

So what predicted atherosclerosis extremely well then? Let's have a look, shall we?

Whoa - big prediction here - very important things to watch - the higher they are, the more atherosclerosis - never fails !!! Note that diabetic physiology underpins most cardiac disease - and idiopathic blood pressure is mostly hyperinsulinemia driven. Go figure ;-)

Whoa - big prediction here - very important things to watch - the higher they are, the more atherosclerosis - never fails !!! Note that diabetic physiology underpins most cardiac disease - and idiopathic blood pressure is mostly hyperinsulinemia driven. Go figure ;-)

And what didn't predict atherosclerosis - and in fact could be highly misleading? Have a look below:

Bum steer there guys..."Cholesterol" can be good when it's low - and bad when it's low too! Don't go by these measures...note around 17% of the super-high CAC group were on Lipid-lowering, versus ~14% of the very-high CAC group - so the poor predictability of "cholesterol" wasn't due to that factor... ;-)

Bum steer there guys..."Cholesterol" can be good when it's low - and bad when it's low too! Don't go by these measures...note around 17% of the super-high CAC group were on Lipid-lowering, versus ~14% of the very-high CAC group - so the poor predictability of "cholesterol" wasn't due to that factor... ;-)

Here's the HR's for the various factors - looks like they were too embarrassed to leave ApoB / LDLp in their table (I think you're simply not allowed to criticize this most recent embodiment of the "Cholesterol Hypothesis"):

Don't forget to subscribe for free at www.thefatemperor.com/subscribe - unless of course you prefer fake news... ;-)