By Jupiter! (Obfuscation Writ Large.....)

I generally focus on the raw science of human health, but I went through a brief period of being interested in some of the major medications out there; to wit - how they compare in efficacy to a properly constructed diet, and the maintenance of critical parameters for healthy physiology such as w6/w3 balance, and 25 Hydroxy Vit D concentration.  Anyway, I haven't the time to collate my findings in this sphere at the moment, but this piece sent to me gives a good summary of the methodology that can underpin major trials; to be sure, results from the latter have a major influence on pharmacological proliferation, and engineers particularly may be interested in the reality of their design and execution - and the surprising inferences taken from them, given that reality. The Jupiter "experience", sadly, is far from unique: