TED Talk from Dr. Rangan Chatterjee: putting Insulin Resistance centre-stage!

Too busy for posts lately, but can't miss this one. I first met Rangan in London last November at Darryl Edward's "Health Unplugged" conference. He appeared out of nowhere, treating me to an enormous handshake - and also his trademark intense authenticity. This guy means everything he says - and he's bang on the money to boot.

Hope you enjoy this excellent TED talk (his first) as much as I did. It's so fulfilling to see the focus moving to genuine root cause resolution. Every doctor needs to view the world as Rangan does; attend to the causes - not the symptoms...! :-)

Please share like hell...and subscribe to www.thefatemperor.com/subscribe too while yer at it... :-)

Note: just as a primer on the importance of Insulin Resistance status, see here what Gerald Reaven saw when he followed ~250 random 60-year-olds for around six years. He split them into low, medium and high Insulin Resistance tertiles up front - guess who got all the bad outcomes? Right:

"The Complete Guide to Fasting" (Dr. Jason Fung / Jimmy Moore) - Book Review !

Let me have men about me that are fat,

Sleek-headed men and such as sleep a-nights.

Yond Cassius has a lean and hungry look.

He thinks too much. Such men are dangerous” (Julius Caesar 1.2.8)

I have long practised the art of fasting; for the weight control benefits sure – but also for the health and mental wellbeing that it affords. On the latter it is much more than mere wellbeing by the way. Fasting enables an extraordinary boost in mental acuity. With no doubt whatsoever, I am at my sharpest and most capable when fasted for about 20 hours or more. Thus I prepare for stressful or challenging situations – by not eating for a long period in advance.

Reading “The Complete Guide to Fasting” was a hugely enjoyable experience. While doing so the above quote from Julius Caesar sprang into my mind. Caesar sees the danger in Cassius, his intellect honed from lack of overfeeding. Deep down might we all like to be Cassius?  Perhaps not the dangerous piece. But certainly the lean and sharp-minded aspects. How do we achieve this state of body and mind? How do we reverse metabolic disease and poor health status? Is it just by old-fashioned calorie-counting, and perhaps getting your macros right (i.e. healthy LCHF)?

I don’t think so. I rather agree with Jason and Jimmy’s premise in this book. The ‘diet-and-exercise’ and ‘eat at regular intervals’ advice has been trotted out for the past 50 years. But the dietary elements (and eating patterns encouraged) flew in the face of evolutionary evidence. With high carbohydrate and regular ‘grainy snacks’, we have spawned an enormous diabetes epidemic (over half of adult Americans are now pre-diabetic or diabetic). The modern population is indeed in a difficult place. It will require a return to evolutionary principles to set us free.

The book lays out all aspects of Fasting’s ancient practice, explaining the science behind the many benefits. It starts off by contrasting the terms ‘starvation’ and ‘fasting’. The former is forced on a person, the latter is by choice. There is an enormous difference. You will however hear people deceitfully use the term ‘starvation’ in order to attack the practice of fasting. Ignore these idiots. We see that fasting essentially switches the fuel source from what you put in your mouth, to what you carry around your middle. The biochemistry is beautiful – elegantly switching to ancient processes of bodyfat oxidation, both healthy and entirely appropriate. Many other biochemical benefits are triggered by fasting, including the positive boost in Human Growth Hormone (HGH). This has a key role in preserving muscle and leads to many other parallel benefits for longevity.

Chapter two covers the fascinating historical background of the practice itself. All religions have fasted in various ways. Nearly all cultures have valued its benefits. Over the past few decades, however, our western industrialised society has consistently undermined the ancient practice. Why is this? Well, the food, advertising and other industries have a huge stake in the consumer society. They care little of the threat from ‘reduce your calories’ (they are well aware that this jaded junk-advice doesn’t work for long). The concept of deploying ancestral wisdom is another matter entirely. To have fasting become a valued and common pursuit…is quite a frightening spectre to the money men. And so it must be rubbished and dismissed as ‘unhealthy and dangerous’.  In chapter three we get an entertaining run-through of all the myths that have been crafted to protect the profits. We also get a super summary of the truth that belies every single myth. I was reminded of the cholesterol myths we have suffered for so long – the same ruinous rulebook has been applied to fasting. We have been made fools of for decades – but now it is time to wake the hell up.

Chapters four brings us on a journey that is as convincing as it is captivating. Have you any idea of the sheer diversity and magnitude of fasting’s advantages? You certainly will after these chapters – and want to start getting hold of them for yourself! What emerges is a picture in stark contrast to what we’ve been told for generations. With fasting the bad gets minimised, the good gets better – across a dizzying array of advantages you can create for yourself. All are lined up like in an ammo belt: Simple, Free, Convenient, Pleasure-Enabling, Powerful, Flexible, …and it works with ANY chosen diet. Explained too is fasting as one of the most powerful tools in the box; it can deal with challenges that are resistant to LCHF and many other approaches – challenges which quail in the face of fasting. It is that powerful. You are free to wield this tool for yourself…after internalising the content of this book.

The next chapters bring us through the profound problems of weight-loss and type 2 diabetes. You guessed it – the power of fasting comes into its own here. Peppered throughout the text are real-life affidavits from Jason’s practice which illustrate what can be achieved. As always, the supporting science is referred to and explained – without slowing the pace with heavy or boring detail. We get to see the enormous benefits which fasting can deliver against Alzheimer’s, Heart Disease and many other modern inflammatory conditions. As mentioned I have been fasting for many years now, and have strong thoughts on the ways in which hunger can be mastered with the right approaches; in chapter nine we get a superb summary of how to do this. Importantly, there are explanations of the mechanisms behind detrimental feelings of hunger – and how they can be sidestepped gracefully. I love it.

Time is pressing so here I will wrap up. There is a comprehensive Section 2 which gives all the protocols for successfully implementing a range of fasting regimes. All common variants are covered carefully, to enable all types of fasting. With this section you can become an expert in the art. You’ll never look back. The final section 3 has a range of delicious recipes, for the times when you are not indulging in the mind and body-enhancing attributes of the ancient remedy.

Get this book, and you too can be a kind of Cassius; lean, focussed and sharp-witted. But without the dangerous streak maybe…unless you like that sort of thing !

The book:  https://www.amazon.co.uk/Complete-Guide-Fasting-Jason-Fung/dp/1628600012/ref=sr_1_1/256-8433904-0165728?ie=UTF8&qid=1478264147&sr=8-1&keywords=complete+guide+to+fasting

..and see my video chat with Jason on the fasting topic here:

Part 1:  https://www.youtube.com/watch?v=kU5bc3Fja34

Part 2:  https://www.youtube.com/watch?v=t6QyQ2svKns

…and don’t forget to subscribe for free at www.thefatemperor.com/subscribe ;-)

Note: the Cassius analogy of course applies equally to male or female participants – no sexism on this site !

Free Preview of Fat Emperor San Diego riff - Heart Disease primary root causes !

FREE PREVIEW of my July #LowCarbUSA talk in San Diego; join up with Diet Doctor and see masses of content which will (enjoyably) extend your productive lifespan...! :-)  - the sneak preview below - subscribe for free at www.thefatemperor.com/subscribe - for always-free content...

Fat Emperor turns up on Christopher Kelly's KETO SUMMIT - enjoy !

Had a great chat with Christopher on his excellent Keto Summit - free registration to watch within next 36 hours at http://ketosummit.com/ ! Click on image below to watch... :-)

Link here also http://ketosummit.com/launch-day-6

Below links to the full summit with many superb speakers and great science - also some other great products that Christopher has produced for minimal price...

Keto Summit Opt-in / Registration:   https://mz164.isrefer.com/go/ketosummit/TheFatEmperor/

Keto Summit - Cancer (Seyfried Video):   https://mz164.isrefer.com/go/cancer-seyfried/TheFatEmperor/

30-Minute Paleo Dessert Recipes: https://mz164.isrefer.com/go/paleo-dessert-recipe/TheFatEmperor/

Essential Keto Cookbook: https://mz164.isrefer.com/go/ekc/TheFatEmperor/

Essential Paleo Cookbook:   https://mz164.isrefer.com/go/epc/TheFatEmperor/

 

Short Informational Video on CAC / Calcium Scanning - dodge that Heart Attack!

A short professional summary of Calcium Scanning technology, and what it can offer to the millions with hidden heart disease. Remember that since 2013, CAC is in the US and European guidelines - recommended for 'middle-risk' people. These are the largest group - where MOST heart attacks occur! So why aren't we using this amazing test, that takes a few minutes - and actually SEES the atherosclerotic disease itself? Well sadly, most doctors (and even cardiologists) have no idea of its power - for business-centric and other reasons. But all potential US Presidents and astronauts MUST have a CAC scan before taking office - because it is the ultimate test for heart disease presence. So don't sell yourself short - your life is as important as those guys, right? At the end of this post is a short primer on the important root causes you can address to resolve atherosclerosis (if your score is indeed high)

For more details see www.IHDA.ie

...and see the riveting Widowmaker Movie at Netflix USA: https://flixsearch.io/movie/the-widowmaker-2015


...or on iTunes: https://itunes.apple.com/ie/movie/the-widowmaker/id960575237

And after seeing the movie, would you still want to depend on 'risk factors' to guess if you have serious heart disease and all-cause mortality risk? Hardly - look at those so-called 'risk factors' versus CAC in predicting death below:

CAC sees the disease - and how bad that disease is:

CAC sees the disease - and how bad that disease is:

You want another view of how powerfully your CAC score predicts death, if you don't take action? Ok then, have a look:

CAC: Nothing comes close in telling you how it is inside

CAC: Nothing comes close in telling you how it is inside

You want to roll the dice with that noisy BS 'Framingham Risk' confection? I wouldn't if I were you - I'd get a CAC scan, and find out where you really stand:

Trust your future to Framingham? You're joking - right?

Trust your future to Framingham? You're joking - right?

How about Aortic calcification predicting disaster events? Yep, no surprises - same story. Makes 'cholesterol' risk look like a sick joke:

Just look at the difference in those survival rates...

Just look at the difference in those survival rates...

Like to see a tiny subset of the CAC /Calcification studies that show how this technology absolutely blows away CIMT and all the other 'risk factors', rendering them redundant? Ok then:

Yeah - that's why CAC is now enshrined in the US and European guidelines for middle-risk (i.e. most) people. It blows away the other fluff-tests.

Yeah - that's why CAC is now enshrined in the US and European guidelines for middle-risk (i.e. most) people. It blows away the other fluff-tests.

Is YOUR life worth as much as a US president or an astronaut. I'm damn sure mine is. I think yours probably is too. Get a scan, and take action if needed - it ain't too hard to fix the big problems - short video below gives you a primer!

Peter Ballerstedt - Forage Agronomist - on the Ruminant Revolution! #LCHF

Nice chat in Corvallis last night with Peter, who has extensive experience in the science of animal feeding practices - and the subsequent impact on their biological makeup. We cover this, the dietary guidelines debacle, low carb for improving health, and a few other topics ! Note that we do not get into the detail here of particular genetic profiles that may have a sensitivity to dairy and other animal products - this is a more general overview of the field... :-)

Please support this and future 'always free' content, by subscribing to www.thefatemperor.com/subscribe (also for free - of course!)

The graphs referred to on omega 6 / omega 3:

Dr. Ted Naiman and Fat Emperor talk chronic disease: tests and solutions ! #LCHF

Caught up with Dr. Ted Naiman (yes, THE Ted Naiman) in Seattle today, and had a chat on some of the key elements that enable long-term health and longevity. Wondering about the most important blood tests? Ok we talked about those. The ideal diet for the human species? Yep - had a few words. The best diagnostic tests for cardiovascular disease? Yup. What about the most optimum (and yet easiest to do) exercise for your health? Hey, we covered that too - and then some !

Supported by www.IHDA.ie - who work to minimise heart disease mortality in the world.

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The mice now speak: Insulin Resistance freed from the confounding of 'cholesterol'

Quick post on some interesting new research sent on to me by Raymund Edwards (thanks Raymund!). Only speed-read it but good to get it out for review. The old cholesterol and atherosclerosis thing has been doing the rounds for decades, while the data points to insulin-related dysfunction being vastly more important. Here we have a team who are helping to remove the 'cholesterol noise' from the insulin picture. I'll simply reproduce Raymund's facebook post in full below. Bottom line is that they've produced a mouse model which separates the 'cholesterol confusion' from the 'insulin resistance imperative'. They have in short demonstrated atherosclerotic acceleration through insulin-mediated action - WITHOUT the cholesterol confounding. Cholesterol metrics gone awry are most often a by-product of insulin/glucose dysfunction, and the 'cholesterol' gets mistaken for cause. So kudos to these researchers - if we had work like this a few decades ago, we might not be suffering the diabetic farce that we are in today...

Don't forget to subscribe for more of the relevant data at www.thefatemperor.com/subscribe

The paper:  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891225/ and Raymund's summary excerpts below:

"Some background to this group headed by Sonia M. Najjar
They have a NUMBER of studies planned

--> Individuals with metabolic diseases are at a higher risk of developing atherosclerosis, a leading cause of death in the United States and worldwide.

Earlier studies have linked dyslipidemia to the initiation and progression of atherosclerosis. However, recent clinical studies raised concerns about the efficacy of lowering plasma cholesterol levels in the progression of atherosclerosis. Although insulin resistance is associated with increased incidence of cardiovascular disease, whether it leads to atherosclerosis independently of its accompanying dyslipidemia remains unclear, largely because of the lack of a suitable animal model to address this question.

The CarcinoEmbryonic Antigen-related Cell Adhesion Molecule-1 (CEACAM1) regulates insulin sensitivity by promoting insulin clearance in liver. Accordingly, global null deletion of Ceacam1 gene impairs hepatic insulin clearance and causes hyperinsulinemia, which in turn, results in systemic insulin resistance.

Preliminary data show: (i) that global Cc1–/– null mice develop early atherosclerotic lesions and vascular dysfunction even under normal feeding conditions, and (ii) that this occurs in the absence of hyperlipidemia, despite VLDL/LDL cholesterol levels that are usually associated with atherosclerosis regression, not development.

This unique animal model of atherogenesis with isolated insulin resistance in the absence of hyperlipidemia demonstrates that systemic insulin resistance resulting from hyperinsulinemia leads to vascular dysfunction and atherosclerosis in the absence of hyperlipidemia.

Because phosphorylation of CEACAM1 by both insulin and VEGF receptors regulates Akt1 activation of endothelial Nitric Oxide Synthase (eNOS), an essential step in mediating endothelial function, it is reasonable to propose that CEACAM1 is the shared downstream element in VEGF and insulin signaling in endothelial cells, whose inactivation impinges upon both pathways and causes endothelial dysfunction in insulin resistance.

==> The CarcinoEmbryonic Antigen-related Cell Adhesion Molecule-1 (CEACAM1) is a membrane with ubiquitous expression in many cell types, including liver and endothelial cells, but not skeletal muscle and adipose tissue. CEACAM1 regulates insulin sensitivity by promoting insulin clearance in liver.

We and others, have shown that mice with global deletion of Ceacam1 gene (Cc1–/–) exhibit hyperinsulinemia, resulting from impaired hepatic insulin clearance. Hyperinsulinemia in these mice leads to insulin resistance, increased liver triglyceride content and de novo lipogenesis, which drive VLDL-ApoB secretion and triglyceride accumulation in adipose tissue, causing visceral obesity and raising serum fatty acid levels. Thus, the Cc1–/– mouse is a
model of hyperinsulinemia causing insulin resistance.

•• Preliminary data show: (i) that Cc1–/– mice with global Ceacam1 deletion spontaneously develop early atherosclerotic lesions with impaired endothelial-dependent vasodilation under normal feeding conditions, and (ii) that this occurs despite VLDL/LDL cholesterol levels that are usually associated with atherosclerosis regression, not initiation.

Therefore, Ceacam1 deficiency causes hyperinsulinemia and insulin resistance, and promotes lipid-independent vascular toxicity. This makes Cc1–/– a unique animal model of spontaneous
atherosclerosis with isolated insulin resistance in the absence of hyperlipidemia, and provides an in vivo demonstration of distinct CEACAM1-dependent mechanisms linking insulin resistance to atherosclerosis.

• Ceacam1 deletion causes vascular alterations in large vessels

CAC Calcium, the ultimate test for Atherosclerosis...challenges LDL as cause!

Just got hold of a great book, and haven't read much yet. However, you're going to enjoy the initial small excerpts I've collated for your pleasure. Native Human Cholesterol/LDL as a significant causal driver of Atherosclerosis? Never made sense to me to be honest. Data doesn't add up at all. But lookee here at what these guys have dug up - read from the top. Read down...and weep. The book is available here ('Atherosclerosis: Risk Factors, Prevention and Treatment'): https://www.novapublishers.com/catalog/product_info.php?products_id=29530

Warning: This material may cause serious damage...to a lipidologist's peace of mind. Read at your own risk! 

As always for more science scoops, please subscribe (free!) www.thefatemperor.com/subscribe

#LDL Cholesterol - A Nastily Misleading 'Risk Factor' #LCHF

Well here we go again - deja vu. Just looking up some stuff on Free Fatty Acids this evening and came across this paper. These guys made the old mistake of measuring LDL in (a) healthy people, (b) Diabetics and (c) Acute Myocardial Infarction victims. Note that for all groups, patients on lipid-lowering drugs were excluded (i.e. this is a proper study, not confounded with meds). And so we get a glimpse of the fat, sweaty Cholesterol Emperor again. Such careless researchers, to let the cat out of the bag like this! Have a look at what did matter between the different types of people (with LDL at top middle, irrelevant as usual):

And below in tabular form - Red boxes show relevant stuff, while the dashed box shows the junk-science distraction-factor....of the industry darling, LDLc:

But did they call out the LDL irrelevancy in their conclusion, and ask some salient scientific questions? No, of course they didn't. Because you're not allowed to question the LDL dogma, or it's bye-bye to your future funding. That's why we've had to endure the LDLc distraction for decades. And these guys did worse than ignore the obvious LDL question in their conclusion piece. Just look at their actual comments on LDL - what a deceitful joke:

Vinnie Tortorich, Fat Emperor and Dr. Jeff Gerber close with part 3...! #LCHF

Here in part three we wrap that sh"t up!  Book Publishing tips? You got it. Performance athletics with low carb and NSNG? Sure thing. Carb-loading BS - yep we cover that too. And then some... :-)

Please also see Peter Defty / Phinney / Volek seminal work here:  http://www.vespapower.com/the-emerging-science-on-fat-adaptation/

Camera & Sound setup: Dr. Jeff Gerber www.denversdietdoctor.com

Supported by www.IHDA.ie

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PART 2 of 3 Below:

And PART 1 of 3 below !

Vinnie Tortorich, Fat Emperor & Dr. Jeff Gerber chat on Malibu Beach - part 2 #LCHF

Here in part two we take off the gloves. "Fat burns in the flame of carbohydrates"? You can lose weight by eating lots of pasta? Medical doctors actually get nutritional training? Who the hell makes up this sh"t - has industry got anything to do with the persistent junk-science? :-)

Camera & Sound setup: Dr. Jeff Gerber www.denversdietdoctor.com

Supported by www.IHDA.ie

Please subscribe for free to www.thefatemperor.com/subscribe - for more free content :-)

PART 1 BELOW - to ease you into it... ;-)

...and final part 3 of 3 below:

Vinnie Tortorich, Fat Emperor & Dr. Jeff Gerber chat on Malibu Beach - part 1 #LCHF

Heeere's Vinnie!

Had breakfast with Vinnie Tortorich and the lovely Serena Scott-Thomas in LA recently. Afterwards we dropped in to Malibu Beach to capture some shenanigans. In part one we get a brief history of Vinnie's troublemaking for the Sugar and Grain industries. We muse on the Diabesity crisis, and wonder how it all went so badly wrong!

Go to www.vinnietortorich.com for more

Camera & Sound: Dr. Jeff Gerber www.denversdietdoctor.com

Supported by www.IHDA.ie

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Part 2 now available below:

...and final part 3 of 3 below:

Dr. Jason Fung and Fat Emperor explore fasting and diabesity - Part 2

Jason doesn't put too fine a point on things, and rightly so - we are living through a public health absurdity, and millions are suffering. Here in part two, we delve deep into the power of fasting. It can quickly resolve fatty liver and T2 diabetes - why aren't people being told we wonder? Jason gets into his stride here, appropriately outraged by the absurdity! Share to help others see the light...

Camera and Sound setup: Dr. Jeffry Gerber www.denversdietdoctor.com

Supported by www.IHDA.ie

( For more free content please subscribe at www.thefatemperor.com/subscribe )

Part one below:

Use the share buttons below as you will... :-)

Dr. Joseph R. Kraft - Stories from the World War II Era - Part 1

On my recent US trip I had the privilege of meeting with Dr. Kraft once more. Father of the Insulin Assay, and one of the most under-recognised greats of medicine and science. Here at aged 95 he talks of old times, relating experiences from World War 2. He was a Medical Captain there, serving mainly in Panama.

He has walked the walk. And he certainly can talk the talk. So how do our modern internet medical gurus compare? What extraordinary history can they relate? What important discoveries have THEY made? Quite.

So please do sit with myself and Dr. Kraft for just a short while. And FEEL the history.

Supported by www.IHDA.ie

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Our July 2015 interview here - on his profound discoveries:

Dr. Jason Fung and Fat Emperor - 'The Fad of Fasting' - Part 1

Dr. Jason Fung gave another great talk at Low Carb USA San Diego. Got to catch up for a chat on camera too. Jason is trying to resurrect for us the superb practice of fasting - the benefits of which have been recognised by ALL of the world's religions for millennia. And rightly so - for metabolic health, neurological health, and to stave off many forms of disease - fasting is one of the best things you can...'indulge in'. I do it all the time - to keep an edge! Here in part one, he introduces the basics. Share this to help counteract our ridiculous 'feed every three hours' corporate culture...!

Camera and Sound setup: Dr. Jeffry Gerber www.denversdietdoctor.com

Supported by www.IHDA.ie

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Part two below:

Use the share buttons below as you will... :-)

WARNING: SALTY LANGUAGE. Those 2 Keto Dudes and Fat Emperor - on Diabetes & KRAFT

Hope you enjoy this podcast on the utter Kraziness of Type 2 Diabetes - and how it could be identified / decimated....decades before those feet have to come off :-(

The following hyperlink has my bit of scientific/engineering outrage expressed reasonably articulately:

Angela Poff PhD and Fat Emperor discuss: #Cancer and Ketogenic Diets #LCHF #Keto

I really enjoyed Angela Poff's informative talk at Low Carb USA San Diego. I then had the privilege of sitting with her for this short discussion. Anglea has been working with Dominic D'Agostino on the interactions between ketogenic diets and cancer metabolism. Here she covers many key points in this exciting arena !  More details of the superb conference last weekend are at www.lowcarbusa.org - get with the low carb revolution... :-)

Camera and Sound setup: Dr. Jeffry Gerber


Supported by www.IHDA.ie

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My interview with the famed cancer researcher Dominic D'Agostino at Low Carb USA is below - Angela works with Dominic to help the next generation grapple more successfully with the modern scourge of cancer - we should support them in any way possible:

Want to know if Type 2 #Diabetes is in your future? Okay then. (part 2)

Another fascinating paper on Insulin Resistance measures from Dr. Tommy Wood & http://icelandichealthsymposium.is/foodloose/. The Swedish guys who did this recent study used an exotic lab measurement of IR (euglycemic insulin clamp), as an alternative to simpler Kraft patterns. They called their algorithm 'CEDER'. They had followed 1049 non-diabetic peeps for >9 years, to see how the CEDER Insulin Resistance level would predict diabetes - and CHD. Here's the incidence rate that occurred for the different CEDER IR levels from 1 to 9. Bottom line: a diagnosis of Type 2 Diabetes should never come as a surprise (my graphics added):

2016 Diabetes CEDER Paper.JPG

Unsurprisingly the Coronary Heart Disease plods along in the diabetic wake. With HR's that yet again make an utter joke of the 'cholesterol' metrics. And remember that these guys were only measured for insulin resistance up front in the study - many of the low IR guys would have developed IR over the years, introducing noise into the picture. Which only goes to make the results even more stunning.

 A diagnosis of Type 2 Diabetes should never come as a surprise - nor should the massive heart disease that comes with it.

My earlier post on this diabetic debacle:  http://www.thefatemperor.com/blog/2016/8/6/want-to-know-if-type-2-diabetes-is-in-your-future-ok-then Also, Kraft details discussion here:

 

You can also see the best way to fix the curse of Hyperinsulinemia/Insulin Resistance here:

Kraft killed this nasty hyperinsulinemia/diabetes response rather effectively. He applied LCHF for starters - all the way back in 1972 !! Dr. Joseph R Kraft - a hero without the recognition...

And lookee here at what Prof Gerald Reaven saw, when he used a similar method of IR measurement. Right - it's in here:

http://www.thefatemperor.com/blog/2015/4/30/insulin-resistance-the-primary-cause-of-coronary-artery-disease-bar-none-lchf?rq=insulin%20resistance

And Dr. Jeff Gerber MD / Amy Savigian MD (with a little help from myself) have generated a poster, to expose some of the absurdity - see here:  http://denversdietdoctor.com/challenging-traditional-cardiovascular-risk-assessment/

Why run after 'cholesterol' in ever-decreasing circles, when there are genuinely accurate measures of risk available? When the elephant is in the goddamn room, and staring you in the face? Why indeed.

(The study featured here: "Comparison between indexes of insulin resistance for risk prediction of cardiovascular diseases or development of diabetes" http://dx.doi.org/10.1016/j.diabres.2015.09.003  )

Please share like hell using the buttons below, or a method of your choosing... ;-)